InQuanto Integrates NVIDIA cuQuantum for Native GPU Support and Prepares for the Era of Quantum Supercomputing
With quantum progress accelerating, we introduce InQuanto v4.0 and explain how it supports customers and researchers exploring the application of AI, HPC and quantum computing – A.K.A. Quantum Supercomputing – to problems in chemistry and related fields
Chemistry plays a central role in the modern global economy, as it has for centuries. From Antoine Lavoisier to Alessandro Volta, Marie Curie to Venkatraman Ramakrishnan, pioneering chemists drove progress in fields such as combustion, electrochemistry, and biochemistry. They contributed to our mastery of critical 21st century materials such as biodegradable plastics, semiconductors, and life-saving pharmaceuticals.
Advances in high-performance computing (HPC) and AI have brought fundamental and industrial science ever more within the scope of methods like data science and predictive analysis. In modern chemistry, it has become routine for research to be aided by computational models run in silico. Yet, due to their intrinsically quantum mechanical nature, “strongly correlated” chemical systems – those involving strongly interacting electrons or highly interdependent molecular behaviors – prove extremely hard to accurately simulate using classical computers alone. Quantum computers running quantum algorithms are designed to meet this need. Strongly correlated systems turn up in potential applications such as smart materials, high-temperature superconductors, next-generation electronic devices, batteries and fuel cells, revealing the economic potential of extending our understanding of these systems, and the motivation to apply quantum computing to computational chemistry.
For senior business and research leaders driving value creation and scientific discovery, a critical question is how will the introduction of quantum computers affect the trajectory of computational approaches to fundamental and industrial science?
Introducing InQuanto v4.0
This is the exciting context for our announcement of InQuanto v4.0, the latest iteration of our computational chemistry platform for quantum computers. Developed over many years in close partnership with computational chemists and materials scientists, InQuanto has become an essential tool for teams using the most advanced methods for simulating molecular and material systems. InQuanto v4.0 is packed with powerful updates, including the capability to incorporate NVIDIA’s tensor network methods for large-scale classical simulations supported by graphical processing units (GPUs).
When researching chemistry on quantum computers, we use classical HPC to perform tasks such as benchmarking, and for classical pre- and post-processing with computational chemistry methods such as density functional theory. This powerful hybrid quantum-classical combination with InQuanto accelerated our work with partners such as , and . Global businesses and national governments alike are gearing up for the use of such hybrid “quantum supercomputers” to become standard practice.
In a recent technical blog post, we explored the rapid development and deployment of InQuanto for research and enterprise users, offering insights for combining quantum and high-performance classical methods with only a few lines of code. Here, we provide a higher-level overview of the value InQuanto brings to fundamental and industrial research teams.
InQuanto v4.0 – under the hood
InQuanto v4.0 is the most powerful version to date of our advanced quantum computational chemistry platform. It supports our users in applying quantum and classical computing methods to problems in chemistry and, increasingly, adjacent fields such as condensed matter physics.
Like previous versions of InQuanto, this one offers state-of-the-art algorithms, methods, and error handling techniques out of the box. Quantum error correction and detection have enabled rapid progress in quantum computing, such as groundbreaking demonstrations in partnership with Microsoft, in April and September 2024, of highly reliable “logical qubits”. Qubits are the core information-carrying components of a quantum computer and by forming them into an ensemble, they are more resistant to errors, allowing more complex problems to be tackled while producing accurate results. InQuanto continues to offer leading-edge quantum error detection protocols as standard and supports users to explore the potential of algorithms for fault-tolerant machines.
InQuanto v4.0 also marks the significant step of introducing native support for tensor networks using GPUs to accelerate simulations. In 2022, ԹϺ and NVIDIA teamed up on one of the quantum computing industry’s earliest quantum-classical collaborations. InQuanto v4.0 introduces classical tensor network methods via an interface with NVIDIA's cuQuantum SDK. Interfacing with cuQuantum enables the simulation of many quantum circuits via the use of GPUs for applications in chemistry that were previously inaccessible, particularly those with larger numbers of qubits.
“Hybrid quantum-classical supercomputing is accelerating quantum computational chemistry research. With ԹϺ’s InQuanto v4.0 platform and NVIDIA’s cuQuantum SDK, InQuanto users now have access to unique tensor-network-based methods, enabling large-scale and high-precision quantum chemistry simulations” - Tim Costa, Senior Director of HPC and Quantum Computing at NVIDIA
We are also responding to our users’ needs for more robust, enterprise-grade management of applications and data, by incorporating InQuanto into ԹϺ Nexus. This integration makes it far easier and more efficient to build hybrid workflows, decode and store data, and use powerful analytical methods to accelerate scientific and technical progress in critical fields in natural science.
Adding further capabilities, we our integration of InQuanto with Microsoft’s Azure Quantum Elements (AQE), allowing users to seamlessly combine AQE’s state-of-the-art HPC and AI methods with the enhanced quantum capabilities of InQuanto in a single workflow. The first end-to-end workflow using HPC, AI and quantum computing was demonstrated using AQE and ԹϺ Systems hardware, achieving chemical accuracy and demonstrating the advantage of logical qubits compared to physical qubits in modeling a catalytic reaction.
Where InQuanto takes us next
In the coming years, we expect to see scientific and economic progress using the powerful combination of quantum computing, HPC, and artificial intelligence. Each of these computing paradigms contributes to our ability to solve important problems. Together, their combined impact is far greater than the sum of their parts, and we recognize that these have the potential to drive valuable computational innovation in industrial use-cases that really matter, such as in energy generation, transmission and storage, and in chemical processes essential to agriculture, transport, and medicine.
Building on our recent hardware roadmap announcement, which supports scientific quantum advantage and a commercial tipping point in 2029, we are demonstrating the value of owning and building out the full quantum computing stack with a unified goal of accelerating quantum computing, integrating with HPC and AI resources where it shows promise, and using the power of the “quantum supercomputer” to make a positive difference in fundamental and industrial chemistry and related domains.
In close collaboration with our customers, we are driving towards systems capable of supporting quantum advantage and unlocking tangible and significant business value.
To access InQuanto today, including ԹϺ Systems and third-party hardware and emulators, visit: /products-solutions/inquanto
To get started with ԹϺ Nexus, which meets all your quantum computing needs across ԹϺ Systems and third-party backends, visit: /products-solutions/nexus
To find out more and access ԹϺ Systems, visit: /products-solutions/quantinuum-systems
About ԹϺ
ԹϺ,the world’s largest integrated quantum company, pioneers powerful quantum computers and advanced software solutions. ԹϺ’s technology drives breakthroughs in materials discovery, cybersecurity, and next-gen quantum AI. With over 500 employees, including 370+ scientists and engineers, ԹϺ leads the quantum computing revolution across continents.
- ԹϺ continues its progress toward fault-tolerant quantum computing, with a series of peer-reviewed breakthroughs in fault-tolerant operations.
- Our progress is not only scientific; it is commercial. By improving logical-qubit reliability and encoding efficiency, ԹϺ is reducing the resource overhead required to scale its quantum computers toward commercially useful workloads.
- These results were achieved on commercial ԹϺ hardware, reinforcing that our architecture is not just setting new standards, but building a practical foundation for customers, partners, and researchers preparing for the fault-tolerant era.
Fault-tolerant quantum computing is the threshold the industry must cross before quantum computers can solve the hardest, highest-value problems with confidence. To be commercially useful at scale, the question is not simply who can build more qubits. It is who can build reliable, efficient, scalable systems that reduce technical risk and accelerate the path to commercial usefulness.
ԹϺ is progressing on that path.
Last year, in partnership with Microsoft, we published a breakthrough in logical computing, demonstrating logical qubits that outperformed their physical counterparts by a factor of 800. We are proud to announce that this work is now being published in Nature, one of the most highly regarded scientific journals in the world.
This work highlights our leading fidelities, as shown in Table 1:
Since then, we’ve accelerated our efforts to reach large-scale fault tolerance and advanced what we believe to be the core building blocks of fault-tolerant quantum computing, from logical-qubit teleportation and multiple error-correction breakthroughs to one of the first meaningful computations using logical qubits. Importantly, these results were achieved on commercial ԹϺ hardware, demonstrating not just scientific progress, but a practical and efficient path toward scalable, customer-ready fault tolerance.
A Recap of Our Recent Technical Progress
Since the work with Microsoft, we achieved a milestone years ahead of schedule, demonstrating high-fidelity teleportation of a logical qubit, which was published in one of the world’s most prestigious journals. Later, we beat our own record in this crucial fault tolerance milestone, thanks to continued improvements to our System Model H2’s fidelity.
Then, a series of results demonstrating more error-correcting milestones (and codes):
- Better than physical results in a ,
- (which significantly reduces resource requirements) in 4 dimensions
- with a concatenated code
- Observed with concatenated codes
- High fidelity magic states and a fully fault tolerant universal gate set in two
Recently, we topped ourselves yet again by performing one of the first meaningful computations with logical qubits – exploring key questions in materials and magnetism, using . This result also includes a leading “encoding rate” squeezing 48 logical qubits out of just 98 physical qubits, emphasizing how our architecture helps to support large scale fault tolerance without enormous resource costs.
It is worth noting that all these results were achieved on our commercial hardware, not on one-off laboratory test-stands – reflecting the performance that we are able to deliver to our customers.
We also did crucial theoretical work, exploring that can reduce resource requirements, time to solution, and shorten the timeline to large scale fault tolerance.
Commercial Implications and the Road Ahead
We believe the commercial implication is clear: ԹϺ is reducing the uncertainty around the path to fault-tolerant quantum computing. Our architecture, hardware fidelity, full-stack control, and error-correction progress are converging into a practical roadmap for systems that can support valuable scientific and commercial workloads.
For those evaluating when quantum computing will become strategically relevant, we believe the signal is also increasingly clear: the fault-tolerant era is no longer a distant concept. It is becoming an engineering reality, and ԹϺ is leading the way.
- University of Southern Denmark (SDU) to use ԹϺ Helios, supported by the Danish e-Infrastructure Consortium (DeiC)
- Access to Helios enables SDU to test and refine fault-tolerant algorithms and error-correction codes under realistic hardware conditions
- The collaboration supports at a scale of 48 logical qubits, positioning Denmark at the forefront of scalable, practical quantum computing
- Researchers exploring the scientific foundations for future development of applications in fields including pharmaceuticals, finance, and defense
Progress in quantum computing is measured by hardware advances plus the algorithms and quantum error-correction codes that turn quantum systems into useful computational tools.
Thanks to recent hardware advances, researchers are increasingly sharpening their tools to probe the performance of quantum algorithms and understand how they behave in realistic conditions – where stability, system architecture and algorithm design all shape performance.
A new Denmark-based collaboration between the University of Southern Denmark (SDU), ԹϺ, and the Danish e-Infrastructure Consortium (DeiC) will utilize ԹϺ Helios. Researchers at the SDU’s Centre for Quantum Mathematics, led by Jørgen Ellegaard Andersen, will use Helios to pursue research into topological quantum computing.
Their work could help explain how and why successful quantum algorithms perform as they do, informing the development of high-performance algorithms suited to emerging quantum systems. They’re exploring the scientific foundations that support future quantum applications across areas including pharmaceuticals, finance, and defense.
“We are thrilled to gain access to ԹϺ’s high-fidelity Helios system. This collaboration gives us a unique opportunity to test the limits of our algorithms and evaluate system performance, while advancing fundamental research and laying the foundation for future applications.”
— Professor Jørgen Ellegaard Andersen, Director of the Centre for Quantum Mathematics at University of Southern Denmark
Why topological methods matter
Topological quantum computing is an area of research that connects quantum computation with deep mathematical structures. It includes the study of error correcting codes known as surface codes that encode quantum information in the global properties of systems of logical qubits.
The research team will explore how these codes behave, and how they may support the development of fault-tolerant quantum algorithms in practical implementations under realistic conditions.
This distinction between theory and practical implementation matters. In theory, topological approaches offer a rich framework for designing algorithms and error-correcting codes. In practice, researchers need to understand how those ideas perform when implemented on real systems, where questions of noise, stability, overhead, and scaling become central. The collaboration will allow the SDU team to investigate these questions directly.
New ways to benchmark quantum processors
Beyond individual algorithms and codes, the research will also develop tools for benchmarking quantum processors. The goal is to develop new ways to characterize fidelity and stability in regimes that can be difficult to access.
The team will also explore hybrid quantum–classical approaches, including machine-learning techniques assisted by quantum hardware, to study the mathematical structures at the heart of topological quantum computing. This work reflects a broader field of research in which quantum and classical methods are used together, each contributing to parts of a computational problem.
Strengthening Denmark’s quantum ecosystem
The collaboration reflects the growing role of national quantum infrastructure in supporting research and talent development. Denmark has a long tradition of scientific innovation, and this collaboration is intended to support the country’s continued development in quantum technology.
The initiative is supported by DeiC, which played a central role in securing funding and enabling access to ԹϺ’s systems. DeiC has been assigned a particular role in developing and coordinating quantum infrastructure initiatives for the benefit of universities and industry, operating without its own commercial, sectoral, or geographical interests. This includes securing dedicated access to quantum computers, producing advisory services and supporting the development of new talent in the Danish quantum sector.
“DeiC’s special effort to secure funding and access for this research initiative is rooted in our organization’s role in relation to the Danish Government’s strategy for quantum technology.”
— Henrik Navntoft Sønderskov, Head of Quantum at Danish e-Infrastructure Consortium
This collaboration promises to accelerate the development of practical algorithms. It is grounded in fundamental science – but its focus is practical: discovering and testing mathematical approaches to topological quantum computing that can be implemented, evaluated, and improved on real quantum hardware.
That work requires both theoretical insight and access to a system such as Helios capable of supporting meaningful scientific work.
This month, ԹϺ welcomed its global user community to the first-ever Q-Net Connect, an annual forum designed to spark collaboration, share insights, and accelerate innovation across our full-stack quantum computing platforms. Over two days, users came together not only to learn from one another, but to build the relationships and momentum that we believe will help define the next chapter of quantum computing.
Q-Net Connect 2026 drew over 170 attendees from around the world to Denver, Colorado, including representatives from commercial enterprises and startups, academia and research institutions, and the public sector and non-profits - all users of ԹϺ systems.
The program was packed with inspiring keynotes, technical tracks, and customer presentations. Attendees heard from leaders at ԹϺ, as well as our partners at NVIDIA, JPMorganChase and BlueQubit; professors from the University of New Mexico, the University of Nottingham and Harvard University; national labs, including NIST, Oak Ridge National Laboratory, Sandia National Laboratories and Los Alamos National Laboratory; and other distinguished guests from across the global quantum ecosystem.
Congratulations to Q-Net Connect 2026 Award Recipients!
The mission of the ԹϺ Q-Net user community is to create a space for shared learning, collaboration and connection for those who adopt ԹϺ’s hardware, software and middleware platform. At this year’s Q-Net Connect, we awarded four organizations who made notable efforts to champion this effort.
- JPMorganChase received the ‘Guppy Adopter Award’ for their exemplary adoption of our quantum programming language, Guppy, in their research workflows.
- Phasecraft, a UK and US-based quantum algorithms startup, received the ‘Rising Star’ award for demonstrating exceptional early impact and advancing science using ԹϺ hardware, which they published in a December 2025 .
- Qedma, a quantum software startup, received the ‘Startup Partner Engagement’ award for their sustained engagement with ԹϺ platforms dating back to our first commercially deployed quantum computer, H1.
- Anna Dalmasso from the University of Nottingham received our ‘New Student Award’ for her impressive debut project on ԹϺ hardware and for delivering outstanding results as a new Q-Net student user.
Congratulations, again, and thank you to everyone who contributed to the success of the first Q-Net Connect!
Become a Q-Net Member
Q-Net offers year‑round support through user access, developer tools, documentation, trainings, webinars, and events. Members enjoy many exclusive benefits, including being the first to hear about exclusive content, publications and promotional offers.
By joining the community, you will be invited to exclusive gatherings to hear about the latest breakthroughs and connect with industry experts driving quantum innovation. Members also get access to Q‑Net Connect recordings and stay connected for future community updates.